Vitamin B6, or pyridoxine, is an important component of the coenzyme PLP, which metabolizes amino acids.175-178 Because of its amino acid transfer ability, the body can produce non-essential amino acids from available amino groups, as well as metabolize protein and urea. Vitamin B6 is essential because of its participation in more than 100 enzymatic reactions, including protein metabolism, conversion of tryptophan to niacin, and neurotransmitter function, among others.179

Found in foods such as eggs, brewer’s yeast, carrots, chicken, fish, brown rice, whole grains, and cabbage, vitamin B6 (along with B12 and folic acid) plays a beneficial role in maintaining already healthy homocysteine levels within normal range.180-183

Please also see Pyridoxal 5’-Phosphate in the Glucose Management section for another form of vitamin B6 that fights glycation reactions.

Some people have reported temporary symptoms of peripheral neuropathy (tingling, numbness sensation, decreased sensation to touch or balance difficulties) when taking vitamin B6 in doses above 300 mg daily, especially if the nutrient is taken without other B complex vitamins. This vitamin should not be taken without co-ingestion of equivalent doses of other B-complex vitamins. Consult your physician before taking this vitamin if you are taking levodopa (L-dopa).